In 2026, poultry producers are facing increasing disease pressure due to climate variability, high-density farming, and reduced antibiotic usage. The shift toward antibiotic-free production has made immunity-focused nutrition a top priority. This is where scientifically formulated poultry feed additives play a critical role.

Recent industry data shows that disease outbreaks can reduce flock productivity by 10–20 percent through poor weight gain, lower egg production, and higher mortality. At the same time, global regulations are limiting antibiotic growth promoters, pushing farms to adopt preventive nutritional strategies instead of reactive treatments.

Modern poultry feed additives are now designed not just for growth, but for immune resilience, gut protection, and pathogen control.

Why Immune-Focused Poultry Feed Additives Matter in 2026

The poultry gut is the first line of defense against pathogens. Around 70 percent of a bird’s immune system is associated with gut health. When digestion is compromised, immunity weakens, increasing susceptibility to infections such as coccidiosis, salmonella, and necrotic enteritis.

Research from 2024–2025 trials indicates that targeted enzyme and probiotic supplementation can improve gut integrity and reduce harmful bacterial load, improving livability by up to 4–6 percent in commercial broiler operations.

Key immune-support benefits of advanced poultry feed additives include:

• Improved gut barrier function
  • Reduced pathogen colonization
  • Enhanced nutrient absorption during stress
  • Stronger antibody response
  • Lower mortality during seasonal challenges

To address these needs, ABTL offers several innovative feed additives that support disease prevention and immune strength.

ADCELL-SBx®

ADCELL-SBx® is a synergistic probiotic-enzyme combination containing:

Mechanism of Action

• boulardii establishes balanced intestinal microflora (Eubiosis) and works via competitive exclusion.
• Produces inhibitory substances such as bacteriocins, fatty acids, and conjugated bile acids.
• Controls colonization of Salmonella, coli, Campylobacter, and Clostridium.
• Secretes 54 kDa protease that proteolyzes Clostridium toxins A & B.
• Stimulates intestinal IgA production (1.8-fold increase in total IgA; 4.4-fold increase in specific anti-toxin A IgA).
• Increases villus height (+65%) and crypt depth (+42%).
• Reduces E. coli and coliforms up to 80%.

Role of Xylanase

• Degrades soluble and insoluble arabinoxylans.
• Reduces gut viscosity.
• Creates suitable environment for probiotic adherence to intestinal mucosa.
• Enhances competitive exclusion efficiency.

Outcome: Lower pathogen load, improved gut immunity, better villi development and nutrient utilization.

AβM Forte™

AβM Forte™ is an endo-1,4-β-D-mannanase based multi-component NSP enzyme complex.

The β-Mannan Challenge

• β-mannans act as PAMPs (Pathogen Associated Molecular Patterns).
• Trigger unnecessary Feed Induced Immune Response (FIIR).
• FIIR consumes approximately 3% of total metabolizable energy.
• Increase digesta viscosity and reduce nutrient absorption.

Mode of Action

• Breaks down β-mannans and other NSPs.
• Reduces viscosity and FIIR.
• Releases trapped nutrients.
• Directs conserved energy towards growth.

Commercial Benefits

• Lower FCR and improved body weight.
• Reduced digesta viscosity.
• Stimulates lipid utilization and amino acid digestibility.
• Improves litter condition.
• Reduces dependency on additives and medication.

BG-MANNAN™

BG-MANNAN™ contains Endo-1,4-β-Mannanase (2,00,000 U/g), produced via fermentation using Trichoderma citrinoviride.

Anti-Nutritional Effects of β-Mannans

• Increase intestinal viscosity.
• Interfere with glucose metabolism.
• Reduce FCR and body weight gain.
• Impact egg production.

Soybean meal contains significant NSP fractions including 1.5–2% β-mannans.

Functional Benefits

• Degrades β-mannans, reducing anti-nutritional effects.
• Improves digestion and absorption of protein, fat, and carbohydrate.
• Enhances glucose absorption and carbohydrate metabolism.
• Stimulates amino acid utilization and protein synthesis.
• Helps regulate immune mechanism and immunity cell production.
• Allows reduction in added oil/M.E. without disturbing nutritional balance.

Recommended dose: 100–200 g/ton
Thermostable up to 90°C.

BIOGRAIN™ SPECIAL CB3

BIOGRAIN™ SPECIAL CB3 is a synergistic blend of:

• Xylanase
  • Glucanase
  • Mannanase
  • Amylase
  • Protease
  • Lipase
  • Phytase
  • Pectinase
  • Cellulase

Manufactured via submerged fermentation technology.

Enzyme Functions

• Protease: Improves amino acid availability by breaking down storage proteins.
• Xylanase: Degrades arabinoxylans, increases ME availability.
• Mannanase: Releases entrapped nutrients.
• Phytase: Releases phosphorus and bound minerals, reducing inorganic P supplementation.
• Cellulase & Pectinase: Reduce digesta viscosity.
• Lipase: Enhances lipid digestion.
• Amylase: Improves starch digestibility.
• Glucanase: Breaks β-glucans.

PRO-MaXYL™

PRO-MaXYL™ is a special enzyme premix for commercial broilers and layers.

Enzyme Composition

• Protease
• Xylanase
• Mannanase
• 6-Phytase

Mode of Action

• Hydrolyses NSPs and reduces feed viscosity.
• Improves nutrient digestibility.
• Enhances protein and carbohydrate digestion.
• Reduces anti-nutritional factors.
• Increases bio-availability of amino acids and phosphorus.

The Future of Poultry Feed Additives in Disease Prevention

As the poultry industry continues moving toward preventive health strategies, immune-supportive poultry feed additives are becoming foundational to successful farm management. Instead of relying on antibiotics after disease appears, producers are investing in nutritional programs that strengthen birds from within.

In 2026 and beyond, farms that integrate enzyme technology, immune modulators, and gut-balancing solutions will be better positioned to reduce disease risk, improve flock uniformity, and protect profitability.

For more insights on innovative poultry nutrition and feed additive solutions, visit ABTL Enzymes.